ENERGY Registry
NCT01056120
Registry to evaluate the clinical performance of the PRO-Kinetic Energy BMS in a large real-world patient population.
Conclusion
- The ENERGY population reflects real-world conditions with bare metal stents (BMS) used mainly in simple lesions.
- In this setting, percutaneous coronary intervention using a cobalt chromium thin-strut BMS with a passive coating showed very good results up to 24 months.
- Results were encouraging with a low composite rate of cardiac death, myocardial infarction (MI) and clinically-driven Target Lesion Revascularization (cd-TLR), even in the pre-defined high-risk groups of diabetes, stents ≤ 2.75 mm and acute coronary syndrome.
Study Design
Prospective, non-randomized, multi-center, observational registry to evaluate the clinical performance of the PRO-Kinetic Energy BMS in a large real-world patient population in standard clinical care.
- Number of patients (n): 1016
- Principal Investigator: Dr. Raimund Erbel, Department of Cardiology, University of Duisburg-Essen, Germany
- Primary endpoint: MACE (Major Adverse Cardiac Events) - composite of cardiac death, cd-TLR, MI and acute myocardial infarction (AMI) at 6 months
- Secondary clinical endpoints (selected): MACE at 12 and 24 months, stent thrombosis (ST) at 6, 12 and 24 months according to ARC definition
![ENERGY study design Picture shows study design](/sites/default/files/migrated_images/bio21787_553x368.jpg)
Primary and main secondary endpoint results at 6, 12 and 24 month
![ENERGY study results Picture shows study results](/sites/default/files/migrated_images/bio21786_1105x300.png)
Comparison of subgroups results at 24 months
![ENERGY subgroup results Picture shows subgroup results](/sites/default/files/migrated_images/bio21789_553x368.jpg)
![ENERGY subgroup results Picture shows subgroup results](/sites/default/files/migrated_images/bio21788_553x368.jpg)
Downloads
![Picture shows PRO-Kinetic Energy](/sites/default/files/styles/site_width/public/migrated_images/bio08800_553x246.jpg?itok=J_q2G53Q)
Vascular Intervention
Cobalt Chromium Coronary Stent System60 μm thin struts for better clinically proven results
![Picture shows PRO-Kinetic Energy](/sites/default/files/styles/site_width/public/migrated_images/bio06224_553x246.jpg?itok=7Fw_WaPN)
Vascular Intervention
Clinical StudyA randomized trial of paclitaxel-eluting balloon after bare metal stent implantation vs. bare metal stent in STEMI
Source:
Erbel R, Eggebrecht H, Roguin A, et al. Prospective, multi-center evaluation of a silicon carbide coated cobalt chromium bare metal stent for percutaneous coronary interventions: Two-year results of the ENERGY Registry. Cardiovasc Revasc Med. 2014; 15 (11): 381–387.
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